A enzima 2-trans-enoil-ACP (COA) redutase de Mycobacterium tuberculosis : inibição por um novo composto e estudos espectroscópicos do seu mecanismo de resistência à hidrazida do ácido isonicotínico

Tuberculosis (TB) is a neglected disease, which continue to be major cause of morbidity and mortality worldwide, killing together around 5 million people each year. Mycolic acids, the hallmark of mycobacteria, are high-molecular-weight α-alkyl, β-hydroxy fatty acids. Biochemical and genetic experime...

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Bibliographic Details
Main Author: Oliveira, Jaim Simoes de
Other Authors: Santos, Diogenes Santiago
Format: Others
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10183/18799