Diagn?stico e tratamento de Tritrichomonas foetus em gatos com diarreia cr?nica

Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2018-05-03T19:48:33Z No. of bitstreams: 1 2016 - Lara Patricia Santos Carrasco.pdf: 1457762 bytes, checksum: 82c38851cf4f7b3e95d40cfbb6f7ddee (MD5) === Made available in DSpace on 2018-05-03T19:48:33Z (GMT). No. of bitstreams: 1 2016 - Lara Patr...

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Bibliographic Details
Main Author: CARRASCO, Lara Patricia Santos
Other Authors: Souza, Helo?sa Justen Moreira de
Format: Others
Language:Portuguese
Published: Universidade Federal Rural do Rio de Janeiro 2018
Subjects:
Online Access:https://tede.ufrrj.br/jspui/handle/jspui/2268
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Summary:Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2018-05-03T19:48:33Z No. of bitstreams: 1 2016 - Lara Patricia Santos Carrasco.pdf: 1457762 bytes, checksum: 82c38851cf4f7b3e95d40cfbb6f7ddee (MD5) === Made available in DSpace on 2018-05-03T19:48:33Z (GMT). No. of bitstreams: 1 2016 - Lara Patricia Santos Carrasco.pdf: 1457762 bytes, checksum: 82c38851cf4f7b3e95d40cfbb6f7ddee (MD5) Previous issue date: 2016-02-16 === Tritrichomonas foetus has been recently recognized as an important cause of diarrhea in various countries. The aim of this study was to diagnose and treat the infection by T. foetus in cats treated at HVPA of UFRRJ, identify the clinical relevance of this parasite, the risk factors, presence of co-infections and clinical response to treatment. In this study, were admitted 100 felines, from different breeds, both sexes and from 16 weeks of age. As inclusion criteria, patients had to have diarrhea history for more than three weeks, with little success of clinical response to treatments previously used. From the stool samples obtained by colon washing or spontaneous defecation it was conducted direct examination of stool, centrifugal flotation technique and real-time PCR. Of the 100 cats selected for this study, 10% had T. foetus infection. Most positive animals were over one year old (70%) and only 30% had up to 1 year old. Cats were 80% purebred and 20% were animals mongrel. The clinical signs present were diarrhea (60%), weight loss (10%), hemoatochezia (30%) and presence of mucus in the stool (20%). Only two animals were positive for the antigen of FeLV virus, and theses showed more severe case of diarrhea. Three animals showed co-infections with other enteropathogens (30%), one with Giardia, one with Cryptosporidium and one with Cystoisospora. All treated animals showed clinical improvement with the administrations of ronidazole at a dose 30mg/kg every 24 hours during 14 days and showed no recurrence until the recent time. We can conclude that T. foetus infection is an important differential diagnosis in cats with chronic diarrhea, which cats of any age and regardless of whether purebred or not, may have the infection, other enteropathogens needs to be investigated in all cases and the treatment was effective in the resolution of clinical signs of all treated cats. === Tritrichomonas foetus foi recentemente reconhecido como um importante agente etiol?gico de diarreia em diversos pa?ses. O objetivo deste estudo foi diagnosticar e tratar a infec??o por T. foetus nos gatos atendidos no HVPA da UFRRJ, identificar a relev?ncia cl?nica deste parasita, os fatores de risco, a presen?a de co- infec??es e resposta cl?nica ao tratamento. Neste trabalho, foram admitidos 100 animais da esp?cie felina, de diferentes ra?as, de ambos os sexos e a partir de 16 semanas de idade. Como crit?rio de inclus?o, os pacientes deveriam apresentar hist?rico de diarreia a mais de tr?s semanas, com pouco sucesso de resposta cl?nica para terap?uticas previamente institu?das. A partir das amostras de fezes obtidas por coleta via lavagem do colon dos animais e pelo ato de defeca??o espont?nea, foram realizados os m?todos do exame direto das fezes, t?cnica de centrifugo flutua??o e PCR em tempo real. Dos 100 gatos que foram selecionados para esta pesquisa, 10% apresentaram infec??o por T. foetus. A maioria dos animais positivos estavam na faixa et?ria acima de um ano (70%) e apenas 30% tinha at? um ano de idade. Os gatos eram 80% de ra?a pura e 20% eram animais sem ra?a definida. Os sinais cl?nicos apresentados por esses gatos foram diarreia (60%), perda de peso (10%), hematoquezia (30%) e presen?a de muco nas fezes (20%). Apenas dois animais infectados eram positivos para o ant?geno do v?rus da FeLV, e estes apresentaram um quadro mais severo de diarreia. Tr?s animais apresentaram coinfec??es com outros enteropat?genos (30%), um com Giardia sp, um com Cryptosporidium e outro com Cystoisospora. Todos os gatos tratados apresentaram melhora cl?nica com a administra??o do f?rmaco ronidazol na dose de 30 mg/Kg a cada 24 horas por 14 dias, n?o apresentando recidiva da diarreia at? o recente momento. Podemos concluir que a infec??o por T. foetus ? um importante diagn?stico diferencial em felinos com diarreia cr?nica, que gatos de qualquer idade e independente de ser de ra?a pura ou n?o, podem apresentar a infec??o, que a co- infec??o com outros enteropat?genos necessita ser investigada em todos os casos e que o tratamento foi efetivo na resolu??o dos sinais cl?nicos de todos os gatos tratados.