Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil

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Main Author:	BOTELHO, Camila Fl?via Magalh?es
Other Authors:	Baldani, Cristiane Divan
Format:	Others
Language:	Portuguese
Published:	Universidade Federal Rural do Rio de Janeiro 2017
Subjects:	Domestic dogs hemoplasmas haematology C?es dom?sticos hematologia Ci?ncias Cl?nicas
Online Access:	https://tede.ufrrj.br/jspui/handle/jspui/2075

id	ndltd-IBICT-oai-localhost-jspui-2075
record_format	oai_dc
collection	NDLTD
language	Portuguese
format	Others
sources	NDLTD
topic	Domestic dogs hemoplasmas haematology C?es dom?sticos hemoplasmas hematologia Ci?ncias Cl?nicas
spellingShingle	Domestic dogs hemoplasmas haematology C?es dom?sticos hemoplasmas hematologia Ci?ncias Cl?nicas BOTELHO, Camila Fl?via Magalh?es Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil
description	Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2017-10-04T18:07:36Z No. of bitstreams: 1 2017 - Camila Fl?via Magalh?es Botelho.pdf: 1531668 bytes, checksum: b445ba2353dc7515e478a8e151b24d75 (MD5) === Made available in DSpace on 2017-10-04T18:07:36Z (GMT). No. of bitstreams: 1 2017 - Camila Fl?via Magalh?es Botelho.pdf: 1531668 bytes, checksum: b445ba2353dc7515e478a8e151b24d75 (MD5) Previous issue date: 2017-02-14 === CAPES === Hemotrophic mycoplasmas hemoparasites are pleomorphic, epicellular, gram negative organisms that are located on the surface of erythrocytes of several species. In dogs, hemoplasma infection can cause hemolytic anemia in the acute phase, while in the chronic phase the signs are generally inapparent, and immunosuppression can trigger the acute disease. The present study aimed to detect molecularly the presence of hemotrophic mycoplasma agents in domestic dogs from the urban and rural areas of Aragua?na, Tocantins and, in addition, to correlate hematological alterations and factors associated with natural infection. In the analysis of the results, 2.9% (3/105) of the dogs sampled from the urban area and 24.49% (24/99) from the rural area were positive for Mycoplasma spp. by the Real Time Polymerase Chain Reaction (qPCR). The frequency of hemoplasmas species infection by PCR using species-specific oligonucleotides was 1.9% (2/105) and 13.26% (13/99) for Mycoplasma haemocanis in the urban and rural areas, respectively. No positive dogs were observed for ?Candidatus Mycoplasma turicensis? and ?Candidatus Mycoplasma haematoparvum?/?Candidatus Mycoplasma haemominutum? in both areas studied. Regarding hematological alterations, there was no statistical association with the infection by Mycoplasma spp. Similarly, among the analyzed variables (age, gender, racial pattern, site cleanliness and housing), no statistical correlation was observed in either urban or rural areas. This is the first report of the molecular detection of Mycoplasma haemocanis in dogs from Tocantins and opens up prospects for future studies in this group of hemotrophic agents. === Os hemoparasitos micoplasmas hemotr?ficos s?o organismos pleom?rficos, epicelulares, Gram negativos, que se localizam na superf?cie dos eritr?citos de diversas esp?cies. Em c?es, a infec??o pelos hemoplasmas pode causar anemia hemol?tica na fase aguda, enquanto na doen?a cr?nica os sinais em geral s?o inaparentes, sendo que a imunossupress?o pode desencadear a doen?a aguda. O presente estudo objetivou detectar molecularmente a presen?a de infec??o pelos agentes micoplasmas hemotr?ficos em c?es dom?sticos procedentes de ?reas urbana e rural de Aragua?na, Tocantins e, adicionalmente correlacionar as altera??es hematol?gicas e fatores associados com a infec??o natural. Na an?lise dos resultados obtidos, 2,9% (3/105) dos c?es amostrados da ?rea urbana e 24,49% (24/99) da ?rea rural foram positivos pela Rea??o em Cadeia da Polimerase em Tempo Real (qPCR) para Mycoplasma spp. A frequ?ncia de infec??o das esp?cies de hemoplasmas pela PCR, utilizando oligonucleot?deos esp?cie-espec?ficos, foi de 1,9 % (2/105) e 13,26% (13/99) para Mycoplasma haemocanis na ?rea urbana e rural, respectivamente. N?o foram observados c?es positivos para ?Candidatus Mycoplasma turicensis? e ?Candidatus Mycoplasma haematoparvum?/?Candidatus Mycoplasma haemominutum? em ambas as ?reas estudadas. No tocante ?s altera??es hematol?gicas, n?o houve associa??o estat?stica com a infec??o por Mycoplasma spp. De modo semelhante, dentre as vari?veis analisadas (idade, sexo, padr?o racial, limpeza do local e moradia) n?o foi verificada qualquer correla??o estat?stica com a infec??o pelo agente Mycoplasma spp., seja na ?rea urbana ou na rural. Esta constitui a primeira detec??o molecular de Mycoplasma haemocanis em c?es do Tocantins e abre perspectivas para futuros estudos neste grupo de agentes hemotr?ficos.
author2	Baldani, Cristiane Divan
author_facet	Baldani, Cristiane Divan BOTELHO, Camila Fl?via Magalh?es
author	BOTELHO, Camila Fl?via Magalh?es
author_sort	BOTELHO, Camila Fl?via Magalh?es
title	Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil
title_short	Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil
title_full	Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil
title_fullStr	Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil
title_full_unstemmed	Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil
title_sort	diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (canis familiaris) nas ?reas urbana e rural de aragua?na, tocantins, brasil
publisher	Universidade Federal Rural do Rio de Janeiro
publishDate	2017
url	https://tede.ufrrj.br/jspui/handle/jspui/2075
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spelling	ndltd-IBICT-oai-localhost-jspui-20752019-01-22T00:51:03Z Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil Molecular diagnostic of haemotropic parasites of dogs (Canis familiaris) under natural conditions of urban and rural areas of Aragua?na, state of Tocantins, Brazil BOTELHO, Camila Fl?via Magalh?es Baldani, Cristiane Divan Baldani, Cristiane Divan Souza, Aline Moreira de Machado, Carlos Henrique Domestic dogs hemoplasmas haematology C?es dom?sticos hemoplasmas hematologia Ci?ncias Cl?nicas Submitted by Jorge Silva (jorgelmsilva@ufrrj.br) on 2017-10-04T18:07:36Z No. of bitstreams: 1 2017 - Camila Fl?via Magalh?es Botelho.pdf: 1531668 bytes, checksum: b445ba2353dc7515e478a8e151b24d75 (MD5) Made available in DSpace on 2017-10-04T18:07:36Z (GMT). No. of bitstreams: 1 2017 - Camila Fl?via Magalh?es Botelho.pdf: 1531668 bytes, checksum: b445ba2353dc7515e478a8e151b24d75 (MD5) Previous issue date: 2017-02-14 CAPES Hemotrophic mycoplasmas hemoparasites are pleomorphic, epicellular, gram negative organisms that are located on the surface of erythrocytes of several species. In dogs, hemoplasma infection can cause hemolytic anemia in the acute phase, while in the chronic phase the signs are generally inapparent, and immunosuppression can trigger the acute disease. The present study aimed to detect molecularly the presence of hemotrophic mycoplasma agents in domestic dogs from the urban and rural areas of Aragua?na, Tocantins and, in addition, to correlate hematological alterations and factors associated with natural infection. In the analysis of the results, 2.9% (3/105) of the dogs sampled from the urban area and 24.49% (24/99) from the rural area were positive for Mycoplasma spp. by the Real Time Polymerase Chain Reaction (qPCR). The frequency of hemoplasmas species infection by PCR using species-specific oligonucleotides was 1.9% (2/105) and 13.26% (13/99) for Mycoplasma haemocanis in the urban and rural areas, respectively. No positive dogs were observed for ?Candidatus Mycoplasma turicensis? and ?Candidatus Mycoplasma haematoparvum?/?Candidatus Mycoplasma haemominutum? in both areas studied. Regarding hematological alterations, there was no statistical association with the infection by Mycoplasma spp. Similarly, among the analyzed variables (age, gender, racial pattern, site cleanliness and housing), no statistical correlation was observed in either urban or rural areas. This is the first report of the molecular detection of Mycoplasma haemocanis in dogs from Tocantins and opens up prospects for future studies in this group of hemotrophic agents. Os hemoparasitos micoplasmas hemotr?ficos s?o organismos pleom?rficos, epicelulares, Gram negativos, que se localizam na superf?cie dos eritr?citos de diversas esp?cies. Em c?es, a infec??o pelos hemoplasmas pode causar anemia hemol?tica na fase aguda, enquanto na doen?a cr?nica os sinais em geral s?o inaparentes, sendo que a imunossupress?o pode desencadear a doen?a aguda. O presente estudo objetivou detectar molecularmente a presen?a de infec??o pelos agentes micoplasmas hemotr?ficos em c?es dom?sticos procedentes de ?reas urbana e rural de Aragua?na, Tocantins e, adicionalmente correlacionar as altera??es hematol?gicas e fatores associados com a infec??o natural. Na an?lise dos resultados obtidos, 2,9% (3/105) dos c?es amostrados da ?rea urbana e 24,49% (24/99) da ?rea rural foram positivos pela Rea??o em Cadeia da Polimerase em Tempo Real (qPCR) para Mycoplasma spp. A frequ?ncia de infec??o das esp?cies de hemoplasmas pela PCR, utilizando oligonucleot?deos esp?cie-espec?ficos, foi de 1,9 % (2/105) e 13,26% (13/99) para Mycoplasma haemocanis na ?rea urbana e rural, respectivamente. N?o foram observados c?es positivos para ?Candidatus Mycoplasma turicensis? e ?Candidatus Mycoplasma haematoparvum?/?Candidatus Mycoplasma haemominutum? em ambas as ?reas estudadas. No tocante ?s altera??es hematol?gicas, n?o houve associa??o estat?stica com a infec??o por Mycoplasma spp. De modo semelhante, dentre as vari?veis analisadas (idade, sexo, padr?o racial, limpeza do local e moradia) n?o foi verificada qualquer correla??o estat?stica com a infec??o pelo agente Mycoplasma spp., seja na ?rea urbana ou na rural. Esta constitui a primeira detec??o molecular de Mycoplasma haemocanis em c?es do Tocantins e abre perspectivas para futuros estudos neste grupo de agentes hemotr?ficos. 2017-10-04T18:07:36Z 2017-02-14 info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/masterThesis BOTELHO, Camila Fl?via Magalh?es Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil. 2017. 50 f. Disserta??o (Mestrado em Medicina Veterin?ria, Ci?ncias Cl?nicas). Instituto de Veterin?ria, Departamento de Medicina e Cirurgia Veterin?ria, Universidade Federal Rural do Rio de Janeiro, Serop?dica, RJ, 2017. https://tede.ufrrj.br/jspui/handle/jspui/2075 por ABINPET. Divulga??o de dados (Pesquisa quinquenal). Dispon?vel em: <http://abinpet.org.br/site/mercado/>. Acesso em 20 de novembro de 2016. ALLISON, R.W.; MEINKOTH, J.H. Anemia caused by Rickettsia, Mycoplasma and Protozoa. 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Tropical Animal Health and Production, v. 41, p. 689?92, 2009. info:eu-repo/semantics/openAccess application/pdf Universidade Federal Rural do Rio de Janeiro Programa de P?s-Gradua??o em Medicina Veterin?ria (Patologia e Ci?ncias Cl?nicas) UFRRJ Brasil Instituto de Veterin?ria reponame:Biblioteca Digital de Teses e Dissertações da UFRRJ instname:Universidade Federal Rural do Rio de Janeiro instacron:UFRRJ

Diagn?stico molecular e avalia??o hematol?gica de micoplasmas hemotr?ficos em c?es dom?sticos (Canis familiaris) nas ?reas urbana e rural de Aragua?na, Tocantins, Brasil

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