Efeito da inibição da clivagem do fator de necrose tumoral (TNF) em modelo de isquemia e reperfusão intestinal

=== TNF-á plays an important role in reperfusion-induced tissue injury and lethality. Here, we assessed the effect of PKF242-484 and PKF241-466, two dual inhibitors of TNF-á converting enzyme (TACE) and matrix metalloproteinases (MMPs). We examine the role of these enzymes modulating TNF-á levels i...

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Bibliographic Details
Main Author: Flavio Lopes Ferreira
Other Authors: Mauro Martins Teixeira
Format: Others
Language:Portuguese
Published: Universidade Federal de Minas Gerais 2007
Online Access:http://hdl.handle.net/1843/MCSC-78FSNE