Regulação da expressão da proteína cinase PKR na ausência de interferons (IFNs) e seu papel na resposta celular mediada por agonistas dos receptores TLR2 e TLR4

=== The role of protein kinase R (PKR) in the antiviral cell state induced by interferons (IFNs) is well known. The increase in its expression in response to stimulation by IFNs results in its autophosphorylation and phosphorylation of its substrate eIF2-alpha. This molecular event interferes with...

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Bibliographic Details
Main Author: Paula Cristiane Motta Sales
Other Authors: Aristobolo Mendes da Silva
Format: Others
Language:Portuguese
Published: Universidade Federal de Minas Gerais 2012
Online Access:http://hdl.handle.net/1843/BUOS-9L7NEM

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