Regulação da expressão da proteína cinase PKR na ausência de interferons (IFNs) e seu papel na resposta celular mediada por agonistas dos receptores TLR2 e TLR4
=== The role of protein kinase R (PKR) in the antiviral cell state induced by interferons (IFNs) is well known. The increase in its expression in response to stimulation by IFNs results in its autophosphorylation and phosphorylation of its substrate eIF2-alpha. This molecular event interferes with...
Main Author: | Paula Cristiane Motta Sales |
---|---|
Other Authors: | Aristobolo Mendes da Silva |
Format: | Others |
Language: | Portuguese |
Published: |
Universidade Federal de Minas Gerais
2012
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Online Access: | http://hdl.handle.net/1843/BUOS-9L7NEM |
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