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Previous issue date: 2016-02-29 === This was a cross-sectional study with the objective to correlate the elevated glycated
hemoglobin levels (HbA1) with blood pressure, handgrip strength and the risk of
cardiovascular disease in children and adolescents with type 1 diabetes mellitus
(T1DM). The sample was composed by approximately 135 volunteers, children and
adolescents aged 12 to 16 years, registered in the specialized research center in diabetes
mellitus, from the Regional Hospital of Taguatinga of the Health Secretary of Federal
District. The anthropometric measures such as: body mass, height and body mass index
(BMI) were done in each appointment by using the growing graph from the National
Center for Health Statistics (NCHS, 2000). Blood pressure and heart rate were
measured by the oscillometric device (Microlife 3AC1-1, Widnau, Switzerland),
according to the recommendations of the The Fourth Report on The Diagnosis,
Evaluation, and Treatment of High Blood Pressure in Children and Adolescents of
2004. To analyze the handgrip strength the mechanic dynamometer Jamar?? (Sammons
Preston Jamar Hand Dynamometer) was used, according to the protocol of Espa??a-
Romero and co-workers (2012). The HbA1 and glucose were mesured by high
performance liquid chromatography (BioRad, Brazil). The lipid profile was determined
by the enzymatic colorimetric method, and the high density lipoproteins were
determined by ionic exchange, followed by colorimetric reaction with the Linco
Research Inc. kit (St. Louis, EUA). The results demonstrated a correlation between
elevated HbA1 levels with alterations in blood pressure, handgrip strength and time of
diagnosis in children and adolescents with T1DM. === Esta pesquisa foi do tipo transversal, com o objetivo de comparar os n??veis elevados da
hemoglobina glicada (HbA1c) com a press??o arterial, for??a de preens??o manual e o
risco de doen??as cardiovasculares em crian??as e adolescentes com diabetes melitos tipo
1 (DM1) . A amostra foi composta de aproximadamente de 135 volunt??rios, crian??as e
adolescentes com idade entre 12 a 16 anos, atendidos no polo de pesquisa, especializado
em diabetes melitos, do Hospital Regional de Taguatinga, da Secretaria de Sa??de do
Distrito Federal. As medidas antropom??tricas como: peso, estatura e ??ndice de massa
muscular (IMC) foram realizadas em cada consulta, usando o gr??fico de crescimento da
National Center for Health Stattistics (NCHS,2000). A press??o arterial e a frequ??ncia
card??aca foram aferidas pelo aparelho oscilom??trico (Microlife 3AC1-1, Widnau,
Switzerland), de acordo com as recomenda????es da (The Fourth Report on The
Diagnosis, Evaluation, and Treatment of High Blood Pressure in Children and
Adolescents, 2004). Para a an??lise da for??a de preens??o manual foi utilizado
dinam??metro mec??nico Jamar?? (Sammons Preston Jamar Hand Dynamometer),
respeitando o protocolo de Espa??a-Romero e colaboradores Para as an??lises sangu??neas
todos pacientes forneceram amostras de sangue, a glicose e a hemoglobina glicada
foram medidas por cromatografia l??quida de alta performance (BioRad, Brasil). O perfil
lip??dico foi medido por m??todo colorim??trico enzim??tico, equipament, para as
lipoprote??nas de alta densidade foram determinadas por troca i??nica, seguidas por
rea????o colorim??trica com kit de Linco Research Inc.(St. Louis, EUA). Os resultados
demonstram a associa????o das concentra????es elevadas da HbA1c com altera????es na
press??o arterial diast??lica, for??a de preens??o manual e tempo de diagn??stico de crian??as
e adolescentes DM1.
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