Qualitative und quantitative Analyse der Phosphorylierung von Proteinen der circadianen Uhr

Qualitative und quantitative Analyse der Phosphorylierung von Proteinen der circadianen Uhr

Die Phosphorylierung als posttranslationale Modifikation von Proteinen spielt bei Signalwegen in Zellen eine große Rolle. Für die Entschlüsselung des molekularen Mechanismus der circadianen Uhr ist es daher von Interesse, die Phosphorylierungsstellen beteiligter Proteine zu identifizieren. Im Rahmen...

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Bibliographic Details
Main Author:	Haaf, Erik
Other Authors:	Linscheid, Michael W.
Format:	Doctoral Thesis
Language:	German
Published:	Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I 2012
Subjects:	Massenspektrometrie circadiane Uhr Proteomics Protein Phosphorylierung Phosphopeptidanreicherung mit TiO2 circadian clock mass spectrometry proteomics protein phosphorylation phosphopeptide enrichment with TiO2 540 Chemie 30 Chemie ddc:540
Online Access:	http://edoc.hu-berlin.de/18452/17230 http://nbn-resolving.de/urn:nbn:de:kobv:11-100203984 http://dx.doi.org/10.18452/16578

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