Periaqueductal Gray Glia Modulate Morphine Tolerance Development via Soluble Tumor Necrosis Factor Signaling
Each year, over 50 million Americans suffer from persistent pain, including debilitating headaches, joint pain, and severe back pain. Although morphine is amongst the most effective analgesics available for the management of severe pain, prolonged morphine treatment results in decreased analgesic ef...
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ScholarWorks @ Georgia State University
2015
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Online Access: | http://scholarworks.gsu.edu/neurosci_diss/17 http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1016&context=neurosci_diss |