Binding of Bisbenzamidines with AT Rich DNA: A Thermodynamic Study

Diamidines are small molecules that generally possess antiparasitic properties and bind preferentially to the minor groove of AT rich DNA. With the goal of getting a better understanding of the thermodynamic driving forces and binding affinities, a series of pentamidine analogs were investigated wi...

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Bibliographic Details
Main Author: Kilpatrick, Nancy A
Format: Others
Published: Digital Archive @ GSU 2011
Subjects:
DNA
ITC
Online Access:http://digitalarchive.gsu.edu/chemistry_theses/41
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1040&context=chemistry_theses