Conformational Bias in 2'-Selenium-Modified Nucleosides and the Effect on Helical Structure and Extracellular Recombinant Protein Production: Current Systems and Applications

Part One. X-ray crystallography has benefited from the synthetic introduction of selenium to different positions within nucleic acids by easing the solving of the phase problem. Interestingly, its addition to the 2' position of the ribose ring also significantly enhances crystal formation. Thi...

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Bibliographic Details
Main Author: Thompson, Richard A
Format: Others
Published: Digital Archive @ GSU 2011
Subjects:
Online Access:http://digitalarchive.gsu.edu/chemistry_theses/37
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1036&context=chemistry_theses