Design and Synthesis of HIF-1 Inhibitors as Anti-cancer Therapeutics

Cancer is responsible for one fourth of the total deaths and is the second leading cause of death, behind heart disease, in the United States. However, there are as many approaches to curing cancer as there are types of cancer. One important issue in solid tumors is hypoxia, a lack of oxygen, which...

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Bibliographic Details
Main Author: Burroughs, Sarah
Format: Others
Published: Digital Archive @ GSU 2013
Subjects:
HIF
Online Access:http://digitalarchive.gsu.edu/chemistry_diss/78
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1078&context=chemistry_diss