Effects of surface chemistry and size on iron oxide nanoparticle delivery of oligonucleotides

The discovery of RNA interference and the increasing understanding of disease genetics have created a new class of potential therapeutics based on oligonucleotides. This therapeutic class includes antisense molecules, small interfering RNA (siRNA), and microRNA modulators such as antagomirs (antisen...

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Bibliographic Details
Main Author: Shen, Christopher
Published: Georgia Institute of Technology 2011
Subjects:
Online Access:http://hdl.handle.net/1853/39520