Design, synthesis, and evaluation of cysteine protease inhibitors
Proteases are enzymes that cleave protein amide bonds. Proteases are involved in a myriad of biological processes and are considered good targets for drug design. The proteases described herein are cysteine proteases, which utilize a cysteine residue thiol to attack the amide carbonyl, leading to...
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Georgia Institute of Technology
2009
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| Online Access: | http://hdl.handle.net/1853/29738 |