Formulation and Optimization of Aliskiren Loaded Poly(Lactide-Co-Glycolide) Nanoparticles
Aliskiren is a non-peptide, orally active renin inhibitor with poor absorption and low bioavailability (~2.6%). In order to improve the current drug delivery system, a commercially available, biodegradable copolymer, poly(lactide-co-glycolide) (PLGA), was employed for a nanoparticle (NP) reformulati...
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Digital Commons @ East Tennessee State University
2015
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| Online Access: | https://dc.etsu.edu/honors/275 https://dc.etsu.edu/cgi/viewcontent.cgi?article=1319&context=honors |