Glutamate Receptor Gene Expression in Human Noradrenergic Neurons: Evidence of Altered Glutamate-Noradrenergic Signaling in Depression and Suicide

Glutamate Receptor Gene Expression in Human Noradrenergic Neurons: Evidence of Altered Glutamate-Noradrenergic Signaling in Depression and Suicide

There is abundant evidence that both glutamatergic and noradrenergic transmission are disrupted in stress-related disorders such as major depressive disorder (MDD). Glutamate provides a major excitatory input to the noradrenergic locus coeruleus (LC), the primary source of norepinephrine in the brai...

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Bibliographic Details
Main Authors: Szebeni, Katalin, Szebeni, Attila, Stockmeier, Craig A., Duffourc, Michelle M., Ordway, Gregory A.
Published: Digital Commons @ East Tennessee State University 2008
Subjects:
depression
suicide
glutamate
noradrenergic
neurons
gene expression
Biomedical Sciences
Online Access:https://dc.etsu.edu/etsu-works/8627

Internet

https://dc.etsu.edu/etsu-works/8627

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