p62-mediated Selective Autophagy Endows Virus-Transformed Cells With Insusceptibility to DNA Damage Under Oxidative Stress
DNA damage response (DDR) and selective autophagy both can be activated by reactive oxygen/nitrogen species (ROS/RNS), and both are of paramount importance in cancer development. The selective autophagy receptor and ubiquitin (Ub) sensor p62 plays a key role in their crosstalk. ROS production has be...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Others |
Published: |
Digital Commons @ East Tennessee State University
2019
|
Subjects: | |
Online Access: | https://dc.etsu.edu/etsu-works/6521 https://dc.etsu.edu/cgi/viewcontent.cgi?article=7772&context=etsu-works |