Quantitative Determination of D- and L- Enantiomers of Methylphenidate in Brain Tissue by Liquid Chromatography-Mass Spectrometry
Methylphenidate, a psychostimulant used for the treatment of attention deficit hyperactivity disorder and narcolepsy, is administered as a 50:50 racemic mixture, despite the fact that d‐methylphenidate has been shown to have greater pharmacologic activity. This paper presents a validated LC‐MS/MS ap...
| Main Authors: | , , , , |
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Digital Commons @ East Tennessee State University
2013
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| Online Access: | https://dc.etsu.edu/etsu-works/5326 https://doi.org/10.1002/bmc.2975 |