Role of Topoisomerase II alpha in DNA Topology and T cell responses during Chronic Viral Infections
The clearance of viruses is largely dependent upon the activation of T cells to generate a robust immune response. However, host responses are suppressed during chronic viral infections. In this thesis, we explored the role of Top2α in DNA topology in individuals with chronic HBV, HCV, and HIV infec...
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Format: | Others |
Language: | English |
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Digital Commons @ East Tennessee State University
2019
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Online Access: | https://dc.etsu.edu/etd/3661 https://dc.etsu.edu/cgi/viewcontent.cgi?article=5121&context=etd |