Role of Topoisomerase II alpha in DNA Topology and T cell responses during Chronic Viral Infections

The clearance of viruses is largely dependent upon the activation of T cells to generate a robust immune response. However, host responses are suppressed during chronic viral infections. In this thesis, we explored the role of Top2α in DNA topology in individuals with chronic HBV, HCV, and HIV infec...

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Bibliographic Details
Main Author: Ogbu, Stella Chinyere
Format: Others
Language:English
Published: Digital Commons @ East Tennessee State University 2019
Subjects:
HIV
HBV
HCV
Online Access:https://dc.etsu.edu/etd/3661
https://dc.etsu.edu/cgi/viewcontent.cgi?article=5121&context=etd