Study on Methods of Simultaneous Multi-Component Analysis.

• Main Author: Ashie, Jennifer Bernice
• Format: Others
• Published: Digital Commons @ East Tennessee State University 2008
• Subjects: UV-visible Spectrophotometry; Copper(II); Iron(III); Multi-Component; Analytical Chemistry; Chemistry; Physical Sciences and Mathematics
• Online Access: https://dc.etsu.edu/etd/1989; https://dc.etsu.edu/cgi/viewcontent.cgi?article=3341&context=etd

Many new instrumentation and different instrumental techniques have been developed to deal with increasing complexity of samples encountered. Many researchers also have coupled these instrumental techniques with chemometric algorithms to assist in the quantitative analysis of multi-component samples in the hope of alleviating the need of tedious separation and cleanup procedures. These newer chemometric procedures tend to be complex and difficult to understand and implement and are successful under different circumstances and conditions. In this study, we start from the very simple beginning and examine the factors that can present difficulties with obtaining the correct results and observe how the system behaves so as to find a better and simpler chemometric procedure to perform mixture quantitative analysis. We have used simulated and actual experimental data obtained from a UV-VIS spectrophotometric measurement of metal complexes to conduct the study. Well understood and defined systems tend to give good results. The main obstacle has been, and still is, interferences in spectral information one gets from the measurement.