Characterization of Sympathetic Ganglion Sensitivity to Substance P in a Genetic and a Non-Genetic Rat Model of Hypertension.

Characterization of Sympathetic Ganglion Sensitivity to Substance P in a Genetic and a Non-Genetic Rat Model of Hypertension.

Intravenous injection of substance P (SP) stimulates sympathetic ganglia to evoke a greater increase in renal sympathetic nerve activity, heart rate (HR) and blood pressure (BP) in hypertensive than normotensive rats due to upregulation of the NK1 receptor. These experiments were designed to determ...

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Bibliographic Details
Main Author:	Tompkins, John Daniel
Format:	Others
Published:	Digital Commons @ East Tennessee State University 2003
Subjects:	DOCA sympathetic ganglia electrophysiology substance P SHR hypertension Medical Sciences Medicine and Health Sciences
Online Access:	https://dc.etsu.edu/etd/855 https://dc.etsu.edu/cgi/viewcontent.cgi?article=2012&context=etd

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