Targeting Histone Deacetylases in Advanced Prostate Cancer

<p>The androgen receptor (AR) signaling axis is a well-established therapeutic target in prostate cancer, due to its central role in tumor maintenance and progression. Although patients respond initially to androgen deprivation therapies and AR antagonists, they invariably progress to a castr...

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Bibliographic Details
Main Author: Brunner, Abigail Maria
Other Authors: McDonnell, Donald P
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10161/9902