DNA-Protein Complexes Created by Mutant EcoRII Methyltransferase and Quinolone Antibiotics in Escherichia coli
<p>Expression of mutant M.EcoRII protein (M.EcoRII-C186A) in Escherichia coli leads to tightly bound DNA-protein complexes (TBCs), located sporadically on the chromosome rather than in tandem arrays. The mechanisms behind the lethality induced by such sporadic TBCs are not well studied, nor is...
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2014
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| Online Access: | http://hdl.handle.net/10161/8713 |