Elucidation of Snm1B Function

<p>The protein Snm1B binds to the telomere binding protein TRF2 to help protect telomeres from DNA damage during S phase. In addition, Snm1B protects DNA from agents that induce interstrand crosslinks (ICLs), lethal lesions that covalently attach the opposite strands of DNA together. To eluc...

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Bibliographic Details
Main Author: Stringer, Jay
Other Authors: Counter, Christopher
Published: 2012
Subjects:
ICL
Online Access:http://hdl.handle.net/10161/5775