Prolyl Isomerase Pin1 Is a Conditional Tumor Suppressor
<p><p>Pin1 specifically binds to and catalyzes the <i>cis-trans</i> isomerization of phosphorylated-Ser/Thr-Pro motifs, which modulate the stability, localization, and function of numerous Pin1 substrates involved in cell cycle and tumorigenesis. During cell cycle progression...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
2011
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10161/5712 |