Development and Characterization of Monovalent and Bivalent RNA Aptamers Targeting the Common Pathway of Coagulation

<p>Anticoagulant agents are commonly used drugs to reduce blood coagulation in acute and chronic clinical settings. Many of these drugs target the common pathway of coagulation because it is critical for thrombin generation and disruption of this portion of the pathway has profound effects on...

Full description

Bibliographic Details
Main Author: Soule, Erin Elizabeth
Other Authors: Sullenger, Bruce A
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10161/12224