I. The Asymmetric Total Synthesis of Apratoxin D II. Studies in the Gold(I)-Catalyzed Cycloisomerization of 7-Aryl-1,6-Enynes. III. Synthesis and Application of Multidentate Ligands Toward the Realization of Fluxional Mechanocatalysis
<p>Apratoxin D, recently isolated from two species of cyanobacteria, L. majuscula and L. sordida, exhibits highly potent in vitro cytotoxicity against H-‐‑460 human lung cancer cells with an IC50 value of 2.6 nM. The potent biological activity exhibited by apratoxin D combined with its intrig...
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2015
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| Online Access: | http://hdl.handle.net/10161/11348 |