Novel Algorithms for Computational Protein Design, with Applications to Enzyme Redesign and Small-Molecule Inhibitor Design
<p>Computational protein design aims at identifying protein mutations and conformations with desired target properties (such as increased protein stability, switch of substrate specificity, or novel function) from a vast combinatorial space of candidate solutions. The development of algorithms...
Main Author: | Georgiev, Ivelin Stefanov |
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Other Authors: | Donald, Bruce R |
Format: | Others |
Language: | en_US |
Published: |
2009
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Subjects: | |
Online Access: | http://hdl.handle.net/10161/1113 |
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