Novel Algorithms for Computational Protein Design, with Applications to Enzyme Redesign and Small-Molecule Inhibitor Design

<p>Computational protein design aims at identifying protein mutations and conformations with desired target properties (such as increased protein stability, switch of substrate specificity, or novel function) from a vast combinatorial space of candidate solutions. The development of algorithms...

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Bibliographic Details
Main Author: Georgiev, Ivelin Stefanov
Other Authors: Donald, Bruce R
Format: Others
Language:en_US
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10161/1113

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