Molekulare Zielstrukturen im Alloxan-induzierten Diabetesmodell der Maus

Molekulare Zielstrukturen im Alloxan-induzierten Diabetesmodell der Maus

Alloxan (ALX) ist ein klassisches Diabetogen, welches in Nagetieren spezifisch pankreatische ß-Zellen zerstört und Symptome induziert, die dem humanen Typ-1-Diabetes vergleichbar sind. Durch eine einmalige, intravenöse (iv) Injektion einer subtoxischen Dosis von 50 mg ALX/kg Körpergewicht (KG) werde...

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Bibliographic Details
Main Author:	Schulte im Walde, Sabine
Other Authors:	Universität Leipzig, Veterinärmedizinische Fakultät
Format:	Doctoral Thesis
Language:	deu
Published:	Universitätsbibliothek Leipzig 2004
Subjects:	Tiermedizin Alloxan Diabetes mellitus Glucosetransporter 2 Glucokinase ddc:620
Online Access:	http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-33556 http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-33556 http://www.qucosa.de/fileadmin/data/qucosa/documents/3355/6.1.pdf

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