Methods for DNA Methylation Sequencing Analysis and their Application on Cancer Data

The fundamental subject of this thesis is the development of tools for the analysis of DNA methylation data as well as their application on bisulfite sequencing data comprising a large number of samples. DNA methylation is one of the major epigenetic modifications. It affects the cytosines of the DN...

Full description

Bibliographic Details
Main Author: Kretzmer, Helene
Other Authors: Universität Leipzig, Fakultät für Mathematik und Informatik
Format: Doctoral Thesis
Language:English
Published: Universitätsbibliothek Leipzig 2016
Subjects:
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-203416
http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-203416
http://www.qucosa.de/fileadmin/data/qucosa/documents/20341/Thesis_HKretzmer.pdf