Large-scale gene expression profiling data of bone marrow stromal cells from osteoarthritic donors

• Main Authors: Stiehler, Maik, Rauh, Juliane, Bünger, Cody, Jacobi, Angela, Vater, Corina, Schildberg, Theresa, Liebers, Cornelia, Günther, Klaus-Peter, Bretschneider, Henriette
• Other Authors: Elsevier,
• Format: Article
• Language: English
• Published: Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden 2017
• Subjects: Knochenmark-Strollzellen; Osteoarthritis; Microarray-Analyse; Gen-Ontologie; Tu Dresden; Publikationsfonds; Bone marrow stroll cells; Microarray analysis; Gene Ontology; Publishing Fund; ddc:570; rvk:WA 15000
• Online Access: http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-217567; http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-217567; http://www.qucosa.de/fileadmin/data/qucosa/documents/21756/main.pdf

This data article contains data related to the research article entitled, "in vitro characterization of bone marrow stromal cells from osteoarthritic donors" [1]. Osteoarthritis (OA) represents the main indication for total joint arthroplasty and is one of the most frequent degenerative joint disorders. However, the exact etiology of OA remains unknown. Bone marrow stromal cells (BMSCs) can be easily isolated from bone marrow aspirates and provide an excellent source of progenitor cells. The data shows the identification of pivotal genes and pathways involved in osteoarthritis by comparing gene expression patterns of BMSCs from osteoarthritic versus healthy donors using an array-based approach.