Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits

Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits

We report the use of thin film poly(dimethylsiloxane) (PDMS) prints for the arrayed mass production of highly uniform 3-D human HT29 colon carcinoma spheroids. The spheroids have an organotypic density and, as determined by 3-axis imaging, were genuinely spherical. Critically, the array density impa...

Full description

Bibliographic Details
Main Authors: Hardelauf, Heike, Frimat, Jean-Philippe, Stewart, Joanna D., Schormann, Wiebke, Chiang, Ya-Yu, Lampen, Peter, Franzke, Joachim, Hengstler, Jan G., Cadenas, Cristina, Kunz-Schughart, Leoni A., West, Jonathan
Other Authors: Royal Society of Chemistry,
Format: Article
Language:English
Published: Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden 2014
Subjects:
Saure Phosphatase
Untersuchung
Zellkultursystem
Hepatozyt
Sphäroide
Topoisomerase
Zellviabilität
Wachstum
Mikrofabrikation
Differenzierung
Camptothecin
acid-phosphatase assay
culture-system
hepatocyte spheroids
topoisomerase-i
cell viability
growth
microfabrication
differentiation
camptothecin
generation
ddc:570
ddc:012
rvk:VA 1120
Online Access:http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-138739
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-138739
http://www.qucosa.de/fileadmin/data/qucosa/documents/13873/10.1039c0lc00089b.pdf

Internet

http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-138739
http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-138739
http://www.qucosa.de/fileadmin/data/qucosa/documents/13873/10.1039c0lc00089b.pdf

Similar Items