In vitro modeling of neuronal ceroid lipofuscinosis (NCL): Patient fibroblasts and their reprogrammed derivatives as human models of NCL
The discovery of resetting human somatic cells via introduction of four transcription factors into an embryonic stem cell-like state that enables the generation of any cell type of the human body has revolutionized the field of medical science. The generation of patient-derived iPSCs and the subsequ...
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| Format: | Doctoral Thesis |
| Language: | English |
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Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden
2013
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| Online Access: | http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-118812 http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-118812 http://www.qucosa.de/fileadmin/data/qucosa/documents/11881/Thesis_Xenia_Lojewski.pdf |