Modeling Cancer Cell Response to Immunotherapy
Significant work has been done modeling cancerous tumor growth and response to therapy under certain simplifying assumptions, specifically, the assumption of spatial homogeneity. We have chosen a spatially heterogenous model for cancer cell growth using a hybrid Lattice-Gas Cellular Automata method....
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ndltd-CLAREMONT-oai-scholarship.claremont.edu-hmc_theses-11672019-10-16T03:06:33Z Modeling Cancer Cell Response to Immunotherapy Harley, Eric Significant work has been done modeling cancerous tumor growth and response to therapy under certain simplifying assumptions, specifically, the assumption of spatial homogeneity. We have chosen a spatially heterogenous model for cancer cell growth using a hybrid Lattice-Gas Cellular Automata method. Cell mitosis, apoptosis, and necrosis are explicitly modeled along with the diffusion of nutrients and a necrotic signal. The model implementation is verified qualitatively and is modified to execute on a parallel computer. 2004-05-01T07:00:00Z text application/pdf https://scholarship.claremont.edu/hmc_theses/164 https://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1167&context=hmc_theses HMC Senior Theses Scholarship @ Claremont Spatial Tumor Growth in Parallel Mathematically Modeling |
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Spatial Tumor Growth in Parallel Mathematically Modeling |
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Spatial Tumor Growth in Parallel Mathematically Modeling Harley, Eric Modeling Cancer Cell Response to Immunotherapy |
description |
Significant work has been done modeling cancerous tumor growth and response to therapy under certain simplifying assumptions, specifically, the assumption of spatial homogeneity. We have chosen a spatially heterogenous model for cancer cell growth using a hybrid Lattice-Gas Cellular Automata method. Cell mitosis, apoptosis, and necrosis are explicitly modeled along with the diffusion of nutrients and a necrotic signal. The model implementation is verified qualitatively and is modified to execute on a parallel computer. |
author |
Harley, Eric |
author_facet |
Harley, Eric |
author_sort |
Harley, Eric |
title |
Modeling Cancer Cell Response to Immunotherapy |
title_short |
Modeling Cancer Cell Response to Immunotherapy |
title_full |
Modeling Cancer Cell Response to Immunotherapy |
title_fullStr |
Modeling Cancer Cell Response to Immunotherapy |
title_full_unstemmed |
Modeling Cancer Cell Response to Immunotherapy |
title_sort |
modeling cancer cell response to immunotherapy |
publisher |
Scholarship @ Claremont |
publishDate |
2004 |
url |
https://scholarship.claremont.edu/hmc_theses/164 https://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1167&context=hmc_theses |
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AT harleyeric modelingcancercellresponsetoimmunotherapy |
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