Modeling Cancer Cell Response to Immunotherapy

Significant work has been done modeling cancerous tumor growth and response to therapy under certain simplifying assumptions, specifically, the assumption of spatial homogeneity. We have chosen a spatially heterogenous model for cancer cell growth using a hybrid Lattice-Gas Cellular Automata method....

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Main Author: Harley, Eric
Format: Others
Published: Scholarship @ Claremont 2004
Subjects:
Online Access:https://scholarship.claremont.edu/hmc_theses/164
https://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1167&context=hmc_theses
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spelling ndltd-CLAREMONT-oai-scholarship.claremont.edu-hmc_theses-11672019-10-16T03:06:33Z Modeling Cancer Cell Response to Immunotherapy Harley, Eric Significant work has been done modeling cancerous tumor growth and response to therapy under certain simplifying assumptions, specifically, the assumption of spatial homogeneity. We have chosen a spatially heterogenous model for cancer cell growth using a hybrid Lattice-Gas Cellular Automata method. Cell mitosis, apoptosis, and necrosis are explicitly modeled along with the diffusion of nutrients and a necrotic signal. The model implementation is verified qualitatively and is modified to execute on a parallel computer. 2004-05-01T07:00:00Z text application/pdf https://scholarship.claremont.edu/hmc_theses/164 https://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1167&context=hmc_theses HMC Senior Theses Scholarship @ Claremont Spatial Tumor Growth in Parallel Mathematically Modeling
collection NDLTD
format Others
sources NDLTD
topic Spatial Tumor
Growth in Parallel
Mathematically Modeling
spellingShingle Spatial Tumor
Growth in Parallel
Mathematically Modeling
Harley, Eric
Modeling Cancer Cell Response to Immunotherapy
description Significant work has been done modeling cancerous tumor growth and response to therapy under certain simplifying assumptions, specifically, the assumption of spatial homogeneity. We have chosen a spatially heterogenous model for cancer cell growth using a hybrid Lattice-Gas Cellular Automata method. Cell mitosis, apoptosis, and necrosis are explicitly modeled along with the diffusion of nutrients and a necrotic signal. The model implementation is verified qualitatively and is modified to execute on a parallel computer.
author Harley, Eric
author_facet Harley, Eric
author_sort Harley, Eric
title Modeling Cancer Cell Response to Immunotherapy
title_short Modeling Cancer Cell Response to Immunotherapy
title_full Modeling Cancer Cell Response to Immunotherapy
title_fullStr Modeling Cancer Cell Response to Immunotherapy
title_full_unstemmed Modeling Cancer Cell Response to Immunotherapy
title_sort modeling cancer cell response to immunotherapy
publisher Scholarship @ Claremont
publishDate 2004
url https://scholarship.claremont.edu/hmc_theses/164
https://scholarship.claremont.edu/cgi/viewcontent.cgi?article=1167&context=hmc_theses
work_keys_str_mv AT harleyeric modelingcancercellresponsetoimmunotherapy
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