Adaptation of Proof of Concepts Into Quantitative NMR Methods : Clinical Application for the Characterization of Alterations Observed in the Skeletal Muscle Tissue in Neuromuscular Disorders
Current quantitative nuclear magnetic resonance (NMR) technics offer biomarkers that allow performing non-invasive longitudinal studies for the follow up of therapeutic trials in neuromuscular disorders (NMD). In contrast to fat degeneration, the mechanisms of inflammation/oedema/necrosis and fibros...
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| Language: | English |
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Université Paris Sud - Paris XI
2014
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| Online Access: | http://tel.archives-ouvertes.fr/tel-01067940 http://tel.archives-ouvertes.fr/docs/01/06/79/40/PDF/VD2_CALDAS_DE_ALMEIDA_ARAUJO_ERICKY_06052014.pdf http://tel.archives-ouvertes.fr/docs/01/06/79/40/ANNEX/VD2_CALDAS_DE_ALMEIDA_ARAUJO_ERICKY_06052014_Synthese_en_francais_Annexes.pdf |