Engineering of Lactic Acid Bacteria strains modulating immune response for vaccination and delivery of therapeutics

Engineering of Lactic Acid Bacteria strains modulating immune response for vaccination and delivery of therapeutics

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The use of Lactic Acid Bacteria (LAB), such as Lactococcus lactis (LL), as DNA delivery vehicles represents an interesting strategy as they are regarded as safe. Wild type (wt) LL or recombinant invasive LL, were able to trigger DNA expression by epithelial cells both in vitro and in vivo. However,...

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Bibliographic Details
Main Author: Azevedo, Marcela
Language:English
Published: Université Paris Sud - Paris XI 2013
Subjects:
[SDV:SA] Life Sciences/Agricultural sciences
[SDV:SA] Sciences du Vivant/Sciences agricoles
Mutated Internalin A
Listeria monocytogenes
Lactococcus lactis
Lactic Acid Bacteria
Invasive lactococci
DNA transfer
Online Access:http://tel.archives-ouvertes.fr/tel-00981946
http://tel.archives-ouvertes.fr/docs/00/98/19/46/PDF/VD2_AZEVEDO_MARCELA_25102013.pdf
http://tel.archives-ouvertes.fr/docs/00/98/19/46/ANNEX/VD2_AZEVEDO_MARCELA_25102013_Synthese_en_francais_Annexes.pdf

Internet

http://tel.archives-ouvertes.fr/tel-00981946
http://tel.archives-ouvertes.fr/docs/00/98/19/46/PDF/VD2_AZEVEDO_MARCELA_25102013.pdf
http://tel.archives-ouvertes.fr/docs/00/98/19/46/ANNEX/VD2_AZEVEDO_MARCELA_25102013_Synthese_en_francais_Annexes.pdf

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