New roles of STAT5 factors in chronic myeloid leukemia cell maintenance
The Chronic Myeloid Leukemia (CML) is a clonal hematopoietic stem cell disorder characterized by the t(9:22) genetic translocation and expression of the oncogenic tyrosine kinase BCR-ABL . A first BCR-ABL Tyrosine Kinase Inhibitor (TKI), Imatinib (IM), was identified that inhibits proliferation of B...
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| Language: | English |
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Université René Descartes - Paris V
2013
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| Online Access: | http://tel.archives-ouvertes.fr/tel-00924475 http://tel.archives-ouvertes.fr/docs/00/92/44/75/PDF/vd_casetti_luana.pdf |