Oncolytic H-1 parvovirus NS1 protein : identifying and characterizing new transcriptional and posttranslational regulatory elements

H 1 parvovirus (H-1PV) is a little single stranded DNA virus that preferentially replicates in a lytic manner in transformed cells due to their expression profile that meets the requirements for the activation of H¬ 1 PV life cycle unlike normal cells. This feature is known as oncotropism. H 1PV gen...

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Bibliographic Details
Main Author: Richard, Audrey
Language:English
Published: Université du Droit et de la Santé - Lille II 2011
Subjects:
Online Access:http://tel.archives-ouvertes.fr/tel-00826936
http://tel.archives-ouvertes.fr/docs/00/82/69/36/PDF/Audrey_-_Richard.pdf