The crucial roles played by HNF1β during kidney development

HNF1β is a transcription factor expressed during nephrogenesis in the ureteric bud and in the tubular epithelia derived from the metanephric mesenchyme. Mutations in HNF1B/MODY5 represent one of the most prevalent human genetic defects responsible for Congenital Abnormalities of Kidney and Urinary T...

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Bibliographic Details
Main Author: Massa, Filippo Maria
Language:English
Published: Université René Descartes - Paris V 2012
Subjects:
Online Access:http://tel.archives-ouvertes.fr/tel-00771435
http://tel.archives-ouvertes.fr/docs/00/77/14/35/PDF/va_Massa_Filippo.pdf