Understanding Co-Translational Protein Targeting and Lithium Dendrite Formation through Free Energy Simulations and Coarse-Grained Models

We describe the application of alchemical free energy methods and coarse-grained models to study two key problems: (i) co-translational protein targeting and insertion to direct membrane proteins to the endoplasmic reticulum for proper localization and folding, (ii) lithium dendrite formation during...

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Bibliographic Details
Main Author: Wang, Connie Yuan-Ying
Format: Others
Published: 2016
Online Access:https://thesis.library.caltech.edu/9733/1/WangConnie2016Thesis.pdf
Wang, Connie Yuan-Ying (2016) Understanding Co-Translational Protein Targeting and Lithium Dendrite Formation through Free Energy Simulations and Coarse-Grained Models. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z97H1GHF. https://resolver.caltech.edu/CaltechTHESIS:05232016-092808469 <https://resolver.caltech.edu/CaltechTHESIS:05232016-092808469>