Engineering and Characterization of Cytochrome P450 Enzymes for Nitrogen-Atom Transfer Reactions
The creation of novel enzyme activity is a great challenge to protein engineers, but nature has done so repeatedly throughout the process of natural selection. I begin by outlining the multitude of distinct reactions catalyzed by a single enzyme class, cytochrome P450 monooxygenases. I discuss the...
Internet
https://thesis.library.caltech.edu/8764/1/Farwell_Thesis_013015.pdfFarwell, Christopher C. (2015) Engineering and Characterization of Cytochrome P450 Enzymes for Nitrogen-Atom Transfer Reactions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9765C71. https://resolver.caltech.edu/CaltechTHESIS:01302015-155404718 <https://resolver.caltech.edu/CaltechTHESIS:01302015-155404718>