Protein-protein recognition: The neonatal Fe receptor and immunoglobulin G
The neonatal Fe receptor (FeRn) binds the Fe portion of immunoglobulin G (IgG) at the acidic pH of endosomes or the gut and releases IgG at the alkaline pH of blood. FeRn is responsible for the maternofetal transfer of IgG and for rescuing endocytosed IgG from a default degradative pathway. We in...
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| Format: | Others |
| Language: | en |
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2001
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| Online Access: | https://thesis.library.caltech.edu/8116/8/Martin%202001.pdf Martin, Warham Lance (2001) Protein-protein recognition: The neonatal Fe receptor and immunoglobulin G. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9ek6-6833. https://resolver.caltech.edu/CaltechTHESIS:03072014-143524462 <https://resolver.caltech.edu/CaltechTHESIS:03072014-143524462> |