Structure-Function Studies of Nicotinic Acetylcholine Receptors Using Unnatural Amino Acids and Synthetic Agonist Analogs
<p>This dissertation primarily describes structure-function studies of the prototypical Cys-loop ligand-gated ion channel, the nicotinic acetylcholine receptors (nAChRs).</p> <p>Agonists that bind nAChRs, including acetylcholine, nicotine, and the smoking cessation drug varenic...
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https://thesis.library.caltech.edu/6728/13/APBlum-Thesis.pdfhttps://thesis.library.caltech.edu/6728/1/APBlum-introduction.pdf
https://thesis.library.caltech.edu/6728/2/APBlum-_CHAPTER_1.pdf
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https://thesis.library.caltech.edu/6728/10/APBlum-_APPENDIX_1.pdf
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Blum, Angela Patricia (2012) Structure-Function Studies of Nicotinic Acetylcholine Receptors Using Unnatural Amino Acids and Synthetic Agonist Analogs. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/KFPV-JN09. https://resolver.caltech.edu/CaltechTHESIS:11042011-173102026 <https://resolver.caltech.edu/CaltechTHESIS:11042011-173102026>