Structural Variations on the Turn Unit of DNA-Binding Hairpin Py-Im Polyamides
Modulation of gene expression by small molecules is a challenge in the field of chemical biology. Hairpin pyrrole-imidazole polyamides are a class of programmable small molecules that bind to the minor groove of DNA, and have been shown to inhibit gene expression by interfering with transcription fa...
Internet
https://thesis.library.caltech.edu/5340/1/entire_thesis_10-30-09.pdfFarkas, Michelle Elizabeth (2010) Structural Variations on the Turn Unit of DNA-Binding Hairpin Py-Im Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RVY7-BR84. https://resolver.caltech.edu/CaltechTHESIS:10192009-145249345 <https://resolver.caltech.edu/CaltechTHESIS:10192009-145249345>