Novel Biological Catalysts: Mutagenesis of RTEM β-Lactamase to Alter Substrate and Catalytic Specificity

Novel Biological Catalysts: Mutagenesis of RTEM β-Lactamase to Alter Substrate and Catalytic Specificity

<p>I have used the techniques of site-directed mutagenesis to study the structural requirements for substrate specificity in RTEM-1 β-lactamase and the evolutionary relationship between the β-lactamases and the D,D carboxypeptidases. The D-Ala-D-Ala carboxypeptidases/transpeptidases (penicilli...

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Bibliographic Details
Main Author: Labgold, Marc Robert
Format: Others
Language:en
Published: 1991
Online Access:https://thesis.library.caltech.edu/2838/1/Labgold_mr_1991.pdf
Labgold, Marc Robert (1991) Novel Biological Catalysts: Mutagenesis of RTEM β-Lactamase to Alter Substrate and Catalytic Specificity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/m8m6-yc79. https://resolver.caltech.edu/CaltechETD:etd-07092007-104132 <https://resolver.caltech.edu/CaltechETD:etd-07092007-104132>

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