Characterizing α-Synuclein Membrane Bound Structure
A feature of Parkinson's disease is the presence of fibrillar protein deposits composed mostly of α-synuclein and calcium ions in the brain’s substantia nigra region. Although α-synuclein is natively unfolded, the N-terminal region of the protein is highly helical in the presence of membrane mi...
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Lai, Bert Tsunyin (2008) Characterizing α-Synuclein Membrane Bound Structure. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ZWH6-3B84. https://resolver.caltech.edu/CaltechETD:etd-05062008-171457 <https://resolver.caltech.edu/CaltechETD:etd-05062008-171457>