Development of Enantioselective Organocatalytic Hydrogenation Methods and Progress toward the Total Synthesis of (+)-Minfiensine
<p>The development of an enantioselective organocatalytic hydrogenation reaction utilizing the LUMO-lowering activation of α,β-unsaturated aldehydes has been developed. This strategy employs an imidazolidinone catalyst to activate the alkene towards conjugate reduction of the pendant β,β-disub...