CDRxAb: Antibody Small-Molecule Conjugates with Computationally Designed Target-Binding Synergy

<p>Antibody-drug conjugates (ADCs), or chimeric modalities in general, combine the advantages and offset the flaws of their constituent parts to achieve a broader target space than traditional approaches of pharmaceutical development. My project combines the concept of ADCs with the full atomi...

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Bibliographic Details
Main Author: Wang, Jingzhou
Published: 2021
Online Access: Wang, Jingzhou (2021) CDRxAb: Antibody Small-Molecule Conjugates with Computationally Designed Target-Binding Synergy. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p0kj-9d56. https://resolver.caltech.edu/CaltechTHESIS:05282021-080632319 <https://resolver.caltech.edu/CaltechTHESIS:05282021-080632319>

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