Approaches to the Total Synthesis of Aplysiatoxin
<p>Approaches to the synthesis of the polyacetate tumor promoter aplysiatoxin (1a) are described. The spiroketal framework was convergently constructed in a heteroatom Diels-Alder cyclization to afford spiroketal 11. The desired spirocenter stereochemistry was achieved, in a key reaction pitti...
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| Format: | Others |
| Language: | en |
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1987
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| Online Access: | https://thesis.library.caltech.edu/11458/2/Dussault_PH_1987.pdf Dussault, Patrick H. (1987) Approaches to the Total Synthesis of Aplysiatoxin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/zta1-3f55. https://resolver.caltech.edu/CaltechTHESIS:04122019-170707466 <https://resolver.caltech.edu/CaltechTHESIS:04122019-170707466> |