Truncated azinomycin analogues intercalate into DNA.

No === The design and synthesis of a potentially more therapeutically-viable azinomycin analogue 4 based upon 3 has been completed. It involved coupling of a piperidine mustard to the acid chloride of the azinomycin chromophore. Both the designed azinomycin analogue 4 and the natural product 3 bind...

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Bibliographic Details
Main Authors: Casely-Hayford, M.A., Pors, Klaus, Patterson, Laurence H., Gerner, C., Neidle, S., Searcey, M.
Language:en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10454/3908

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