Hydrogen peroxide-mediated oxidative stress disrupts calcium binding on calmodulin: more evidence for oxidative stress in vitiligo

No === Patients with acute vitiligo have low epidermal catalase expression/activities and accumulate 10 -3 M H 2O 2. One consequence of this severe oxidative stress is an altered calcium homeostasis in epidermal keratinocytes and melanocytes. Here, we show decreased epidermal calmodulin expression i...

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Bibliographic Details
Main Authors: Wood, John M., Gibbons, Nick C., Abou Elloof, M.M., Schallreuter, Karin U.
Language:en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/10454/3001

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